Mabel Amanda Wilcox was born in Sandusky, Ohio on March 4, 1878, to Mr. and Mrs. R. M. Wilcox. On February 7, 1906, Mabel A. Wilcox married Harry M. Orwig. Mr. Orwig was a native of Mansfield, Ohio. A New York passenger list shows the dates of birth of the children of Mabel and Harry M. Orwig.
Mabel's son H. Mercer Orwig was born in 1907. Her daughter Helen was born in 1910; and her daughter Mary was born in 1913. In the 1940 U.S. Census, Harry and Mabel and their son were all living in St. Louis County, Missouri, where the elder Harry M. Orwig owned and operated an interior decorating business. Harry M. Orwig died in 1954. Harry Mercer Orwig, the son of Mabel and Harry, died during World War Two, while serving in the military. According to the U.S. Social Security Death Index, Mrs. Mabel Wilcox Orwig died in Missouri in August of 1978, at the age of 100. Her remains were brought back to Ohio, for burial at Sandusky's Oakland Cemetery. A listing for Mabel Orwig in the Lineage Book of the Daughters of the American Revolution traces her family tree back to Sergent John Hubbard of Connecticut.